Diabetes Mellitus Comorbid with Metabolic Syndrome in New Karachi Township: Prevalence, Risk Analysis, and Future Perspectives

Humera Ishaq, Baqir S. Naqvi, Humera Sarwar, Ata-Ur-Rehman

Abstract

This study aimed to determine the prevalence of metabolic syndrome in known diabetic patients attending diabetes outpatient departments in a tertiary care hospital and to determine the effect of its presence on different body parameters and risk of diabetic complications. This is the first study conducted in the target population of New Karachi Township. Diabetes mellitus correlates with insulin resistance, which results in the development of metabolic syndrome, thus contributing to diabetic complications. This cross-sectional study involved purposive sampling in a tertiary care hospital for 17 months. The ethical committee of the government hospital approved the protocol. After obtaining the consent, participants were interviewed, examined, and asked for blood and urine samples after 14 hours. The prevalence of metabolic syndrome in known diabetic patients was 60%, with body mass index (p < 0.05), blood pressure (p < 0.001), triglycerides (p < 0.001), and fasting sugar (p < 0.05) as positive risk factors and female preponderance. Metabolic syndrome was an independent risk factor for diabetic neuropathy (p = 0.005) and nephropathy (p = 0.014). The metabolic syndrome relates to diabetes mellitus, and developing this correlation in the Pakistani population at large scale study along with proper counseling and awareness campaigns are of utmost importance. The government should take efficient measures to improve the living standards of the low-income group.

 

Keywords: diabetes mellitus, complications, metabolic syndrome, cross-sectional study.

 

https://doi.org/10.55463/issn.1674-2974.51.2.6


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