Association between Clinical, Radiological, and Psychiatric Symptoms in Patients with COVID-19

Alfian Nur Rosyid, Izzatul Fitriyah, Anggraini Dwi Sensusiati, Bagus Aulia Mahdi, Choirina Windradi, Arina Dery Puspitasari

Abstract

So far, COVID-19 is still considered a pandemic worldwide with various clinical, radiological, and psychiatric features. The aim of this study is to assess the correlation among these features. We performed an observational study on patients who have been diagnosed with COVID-19 to analyze their clinical symptoms using the simplified Radiographic Assessment of Lung Edema score and Mini International Neuropsychiatric Interview (MINI ICD-10 version). A total of 50 patients with COVID-19 were included in this study. Generally, COVID-19 infection may entail various symptoms, such as dyspnea, cough, fever, anosmia, diarrhea, vomiting, joint pain, and loss of consciousness. Panic disorder (38% of the cases) is significantly related to the clinical symptoms and severity of the disease (r = 0.29, p = 0.032 versus r = 0.3, p = 0.027). However, no significant association has been found with the severity of radiological and psychiatric problems. COVID-19 infection also entails various psychiatric problems, with panic disorder being the most common problem related to the symptoms and severity of the disease. Influential variables affecting these conditions may also result from acute illnesses due to COVID-19 symptoms, comorbidities, and environmental factors.

 

 

Keywords: clinical symptoms, radiological symptoms, psychiatric symptoms, COVID-19.

 


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References


WORLDOMETER. COVID-19 Coronavirus Pandemic, 2020. https://www.worldometers.info/coronavirus/

KUMAR M., TAKI K., GAHLOT R., SHARMA A., and DHANGAR K. A chronicle of SARS-CoV-2: Part-I - Epidemiology, diagnosis, prognosis, transmission and treatment. Science of the Total Environment, 2020, 734: 139278. https://doi.org/10.1016/j.scitotenv.2020.139278

DAI W. C., ZHANG H. W., YU J., XU H. J., CHEN H., LUO S. P., ZHANG H., LIANG L. H., WU X. L., LEI Y., and LIN F. CT Imaging and Differential Diagnosis of COVID-19. Canadian Association of Radiologists Journal, 2020, 71(2): 195-200. https://doi.org/10.1177/0846537120913033

MUHAMMAD H., AZIZA GHANIE I., ANNISA DIAN H., RIZKY A., FEBRINA S., and LOURISA E. Clinical, Radiological Features and Outcome of COVID-19 patients in a Secondary Hospital in Jakarta, Indonesia. The Journal of Infection in Developing Countries, 2020, 14(7): 750-757. https://doi.org/10.3855/jidc.12911

SHI H., HAN X., JIANG N., CAO Y., ALWALID O., GU J., FAN Y., and ZHENG C. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. The Lancet Infectious Diseases, 2020, 20(4): 425-434. https://doi.org/10.1016/S1473-3099(20)30086-4

COZZI D., ALBANESI M., CAVIGLI E., MORONI C., BINDI A., LUVARÀ S., LUCARINI S., BUSONI S., MAZZONI L. N., and MIELE V. Chest X-ray in new Coronavirus Disease 2019 (COVID-19) infection: findings and correlation with clinical outcome. La radiologia medica, 2020, 125(8): 730-737. https://doi.org/10.1007/s11547-020-01232-9

WARREN M. A., ZHAO Z., KOYAMA T., BASTARACHE J. A., SHAVER C. M., SEMLER M. W., RICE T. W., MATTHAY M. A., CALFEE C. S., and WARE L. B. Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS. Thorax, 2018, 73(9): 840-846. https://doi.org/10.1136/thoraxjnl-2018-212393

MALDONADO J. R. Delirium pathophysiology: An updated hypothesis of the etiology of acute brain failure. International Journal of Geriatric Psychiatry, 2018, 33(11): 1428-1457. https://doi.org/10.1002/gps.4823

CULLEN W., GULATI G., and KELLY B. D. Mental health in the COVID-19 pandemic. QJM, 2020, 113(5): 311-312. https://doi.org/10.1093/qjmed/hcaa110

MATTACE-RASO F., POLINDER-BOS H., OOSTERWIJK B., VAN BRUCHEM-VISSER R., GOUDZWAARD J., OUDSHOORN C., ZIERE G., and EGBERTS A. Delirium: A Frequent Manifestation in COVID-19 Older Patients. Clinical Interventions in Aging, 2020, 15: 2245-2247. https://doi.org/10.2147/CIA.S280189

TAQUET M., LUCIANO S., GEDDES J. R., and HARRISON P. J. Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62354 COVID-19 cases in the USA. The Lancet Psychiatry, 2021, 8(2): 130-140. https://doi.org/10.1016/S2215-0366(20)30462-4

BURHAN E., SUSANTO A. D., NASUTION S. A., GINANJAR E., PITOYO C. W., and SUSILO A. Pedoman Tatalaksana COVID-19. 3rd ed. Perhimpunan Dokter Paru Indonesia, Perhimpunan Dokter Spesialis Kardiovaskular Indonesia, Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia, Perhimpunan Dokter Anestesiologi dan Terapi Intensif Indonesia, Ikatan Dokter Anak Indonesia, Jakarta, 2020. https://www.papdi.or.id/download/983-pedoman-tatalaksana-covid-19-edisi-3-desember-2020

SALARI N., HOSSEINIAN-FAR A., JALALI R., VAISI-RAYGANI A., RASOULPOOR S., MOHAMMADI M., RASOULPOOR S., and KHALEDI-PAVEH B. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis. Globalization and Health, 2020, 16(1): 57. https://doi.org/10.1186/s12992-020-00589-w

BURKE T., BERRY A., TAYLOR L. K., STAFFORD O., MURPHY E., SHEVLIN M., MCHUGH L., and CARR A. Increased Psychological Distress during COVID-19 and Quarantine in Ireland: A National Survey. Journal of Clinical Medicine, 2020, 9(11): 3481. https://doi.org/10.3390/jcm9113481

MAZZA M. G., DE LORENZO R., CONTE C., POLETTI S., VAI B., BOLLETTINI I., MELLONI E. M. T., FURLAN R., CICERI F., ROVERE-QUERINI P., COVID-19 BIOB OUTPATIENT CLINIC STUDY GROUP, and BENEDETTI F. Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors. Brain, Behavior, and Immunity, 2020, 89: 594-600. https://doi.org/10.1016/j.bbi.2020.07.037

ZHANG Y., & MA Z. F. Impact of the COVID-19 Pandemic on Mental Health and Quality of Life among Local Residents in Liaoning Province, China: A Cross-Sectional Study. International Journal of Environmental Research and Public Health, 2020, 17(7): 2381. https://doi.org/10.3390/ijerph17072381

SARASWATHI I., SAIKARTHIK J., SENTHIL KUMAR K., MADHAN SRINIVASAN K., ARDHANAARI M., and GUNAPRIYA R. Impact of COVID-19 outbreak on the mental health status of undergraduate medical students in a COVID-19 treating medical college: a prospective longitudinal study. PeerJ, 2020, 8: e10164. https://doi.org/10.7717/peerj.10164

SHAUKAT N., ALI D. M., and RAZZAK J. Physical and mental health impacts of COVID-19 on healthcare workers: a scoping review. International Journal of Emergency Medicine, 2020, 13(1): 40. https://doi.org/10.1186/s12245-020-00299-5

MAFRUCHATI M. Global Big Data confirm Remdesivir to be a Recommended Antiviral Drug to Fight COVID-19. Journal of Southwest Jiaotong University, 2020, 55(4). https://doi.org/10.35741/issn.0258-2724.55.4.43


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